$75,350 a year$36 an hour · median pay in the Sioux Falls, SD-MN area
Lower pay (bottom 10%)$54,040per year
Top pay (top 10%)$97,330per year
Jobs in the area7,680people work this job
Can a registered nurse afford Sioux Falls?
OK. Rent of $1,314 a month takes 20.9% of the median registered nurse salary. That is under the 30% rule, so one paycheck covers rent comfortably.
Registered Nurse pay in similar cities
Other jobs in Sioux Falls
Nurse PractitionerLicensed Practical NurseNursing AssistantMedical AssistantPharmacistPhysician AssistantDental HygienistElementary School TeacherSoftware DeveloperComputer Systems AnalystAccountantMarket Research AnalystOperations ManagerLawyer
Frequently asked questions
How much does a registered nurse make in Sioux Falls, SD?
The median pay for a registered nurse in the Sioux Falls, SD-MN area is $75,350 a year ($36 an hour). Most earn between $54,040 and $97,330.
Can a registered nurse afford to live in Sioux Falls?
Typical rent of $1,314 a month takes 20.9% of the median registered nurse salary, which we rate OK.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the Sioux Falls, SD-MN metro area.