Registered Nurse salaries › Sioux Falls, SD

How much does a Registered Nurse make in Sioux Falls, SD?

$75,350 a year$36 an hour · median pay in the Sioux Falls, SD-MN area
Lower pay (bottom 10%)$54,040per year
Top pay (top 10%)$97,330per year
Jobs in the area7,680people work this job

Can a registered nurse afford Sioux Falls?

OK. Rent of $1,314 a month takes 20.9% of the median registered nurse salary. That is under the 30% rule, so one paycheck covers rent comfortably.

Registered Nurse pay in similar cities

Sioux Falls
$75,350
$131,160
$79,490

Other jobs in Sioux Falls

Nurse PractitionerLicensed Practical NurseNursing AssistantMedical AssistantPharmacistPhysician AssistantDental HygienistElementary School TeacherSoftware DeveloperComputer Systems AnalystAccountantMarket Research AnalystOperations ManagerLawyer

Frequently asked questions

How much does a registered nurse make in Sioux Falls, SD?

The median pay for a registered nurse in the Sioux Falls, SD-MN area is $75,350 a year ($36 an hour). Most earn between $54,040 and $97,330.

Can a registered nurse afford to live in Sioux Falls?

Typical rent of $1,314 a month takes 20.9% of the median registered nurse salary, which we rate OK.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the Sioux Falls, SD-MN metro area.