salary$130,390 a year$63 an hour · median pay in the Sioux Falls, SD-MN area
Lower pay (bottom 10%)$104,220per year
Top pay (top 10%)$159,330per year
Jobs in the area500people work this job
Can a nurse practitioner afford Sioux Falls?
Cheap. Rent of $1,314 a month takes 12.1% of the median nurse practitioner salary. That is under the 30% rule, so one paycheck covers rent comfortably.
Nurse Practitioner pay in similar cities
Other jobs in Sioux Falls
Registered NurseLicensed Practical NurseNursing AssistantMedical AssistantPharmacistPhysician AssistantDental HygienistElementary School TeacherSoftware DeveloperComputer Systems AnalystAccountantMarket Research AnalystOperations ManagerLawyer
Frequently asked questions
How much does a nurse practitioner make in Sioux Falls, SD?
The median pay for a nurse practitioner in the Sioux Falls, SD-MN area is $130,390 a year ($63 an hour). Most earn between $104,220 and $159,330.
Can a nurse practitioner afford to live in Sioux Falls?
Typical rent of $1,314 a month takes 12.1% of the median nurse practitioner salary, which we rate Cheap.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the Sioux Falls, SD-MN metro area.