salary$135,790 a year$65 an hour · median pay in the Sioux Falls, SD-MN area
Lower pay (bottom 10%)$106,660per year
Top pay (top 10%)$158,520per year
Jobs in the area290people work this job
Can a physician assistant afford Sioux Falls?
Cheap. Rent of $1,314 a month takes 11.6% of the median physician assistant salary. That is under the 30% rule, so one paycheck covers rent comfortably.
Physician Assistant pay in similar cities
Other jobs in Sioux Falls
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Frequently asked questions
How much does a physician assistant make in Sioux Falls, SD?
The median pay for a physician assistant in the Sioux Falls, SD-MN area is $135,790 a year ($65 an hour). Most earn between $106,660 and $158,520.
Can a physician assistant afford to live in Sioux Falls?
Typical rent of $1,314 a month takes 11.6% of the median physician assistant salary, which we rate Cheap.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the Sioux Falls, SD-MN metro area.