$43,760 a year$21 an hour · median pay in the Sioux Falls, SD-MN area
Lower pay (bottom 10%)$36,700per year
Top pay (top 10%)$49,540per year
Jobs in the area620people work this job
Can a medical assistant afford Sioux Falls?
Expensive. Rent of $1,314 a month takes 36.0% of the median medical assistant salary. That is over the 30% rule, so many people in this job share housing or need a second income.
Medical Assistant pay in similar cities
Other jobs in Sioux Falls
Registered NurseNurse PractitionerLicensed Practical NurseNursing AssistantPharmacistPhysician AssistantDental HygienistElementary School TeacherSoftware DeveloperComputer Systems AnalystAccountantMarket Research AnalystOperations ManagerLawyer
Frequently asked questions
How much does a medical assistant make in Sioux Falls, SD?
The median pay for a medical assistant in the Sioux Falls, SD-MN area is $43,760 a year ($21 an hour). Most earn between $36,700 and $49,540.
Can a medical assistant afford to live in Sioux Falls?
Typical rent of $1,314 a month takes 36.0% of the median medical assistant salary, which we rate Expensive.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the Sioux Falls, SD-MN metro area.