salary$83,180 a year$40 an hour · median pay in the St. Louis, MO-IL area
Lower pay (bottom 10%)$63,440per year
Top pay (top 10%)$104,460per year
Jobs in the area35,200people work this job
Can a registered nurse afford St. Louis?
Cheap. Rent of $1,297 a month takes 18.7% of the median registered nurse salary. That is under the 30% rule, so one paycheck covers rent comfortably.
Registered Nurse pay in similar cities
Other jobs in St. Louis
Nurse PractitionerLicensed Practical NurseNursing AssistantMedical AssistantPharmacistPhysician AssistantDental HygienistElementary School TeacherSoftware DeveloperComputer Systems AnalystAccountantMarket Research AnalystOperations ManagerLawyer
Frequently asked questions
How much does a registered nurse make in St. Louis, MO?
The median pay for a registered nurse in the St. Louis, MO-IL area is $83,180 a year ($40 an hour). Most earn between $63,440 and $104,460.
Can a registered nurse afford to live in St. Louis?
Typical rent of $1,297 a month takes 18.7% of the median registered nurse salary, which we rate Cheap.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, for the St. Louis, MO-IL metro area.